ARID1A Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 20652-1-AP

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Freight/Packing

Con: 43 μg/150 μl

Choose size:

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Species specificity:
human

Positive WB detected in:
SKOV-3 cells

Recommended dilution:
WB : 1:200-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
AT rich interactive domain 1A (SWI-like)

Calculated molecular weight:
242 kDa

Observed molecular weight:
22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARID1A

Synonyms
ARID1A, B120, BAF250, BAF250a, BM029, BRG1 associated factor 250, BRG1 associated factor 250a, C1orf4, hELD, hOSA1, Osa homolog 1, OSA1, P270, SMARCF1, SWI like protein, SWI/SNF complex protein p270
Background

ARID1A, also named as BAF250, BAF250A, C1orf4, OSA1 and SMARCF1, is involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). It binds DNA non-specifically. It is also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. ARID1A belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The antibody is specific to ARID1A.


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