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  • KD/KO Validated

Beta Arrestin 1 Polyclonal antibody

Beta Arrestin 1 Polyclonal Antibody for WB, IP, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 15361-1-AP


ARB1, ARR1, ARRB1, Arrestin beta 1, arrestin, beta 1, Beta arrestin 1, β-Arrestin-1

Tested Applications

Positive WB detected inHEK-293 cells, A549 cells, U-937 cells, rat lung tissue, mouse lung tissue, RAW 264.7 cells
Positive IP detected inmouse lung tissue
Positive IHC detected inhuman tonsillitis tissue, mouse spleen tissue, mouse cerebellum tissue, mouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

15361-1-AP targets Beta Arrestin 1 in WB, IP, IF, IHC, CoIP, ChIP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Beta Arrestin 1 fusion protein Ag7608
Full Name arrestin, beta 1
Calculated Molecular Weight 47 kDa
Observed Molecular Weight47-55 kDa
GenBank Accession NumberBC003636
Gene Symbol ARRB1
Gene ID (NCBI) 408
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

β-Arrestins (ARRBs), the best known regulators of G protein-coupled receptor signaling, are versatile and multifunctional adapter proteins that regulate diverse cellular functions, including cell growth, apoptosis and immune responses. Overexpression of beta Arrestin 1 has been found in various cancers, indicating it as a potential therapeutic target for cancer treatment. Recently expression of ARRB1 in saliva has been identified as a candidate circadian biomarker. ARRB1 migrated as a doublet of two bands of 45 and 55 kDa (PMID:28947386).


Product Specific Protocols
WB protocol for Beta Arrestin 1 antibody 15361-1-APDownload protocol
IHC protocol for Beta Arrestin 1 antibody 15361-1-APDownload protocol
IP protocol for Beta Arrestin 1 antibody 15361-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Cell Metab

Autonomous sensing of the insulin peptide by an olfactory G protein-coupled receptor modulates glucose metabolism.

Authors - Jie Cheng
  • KD Validated

J Cell Biol

BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone.

Authors - Fan Ye

Cell Death Dis

β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.

Authors - J Liu

J Biol Chem

An ionic lock and a hydrophobic zipper mediate the coupling between an insect pheromone receptor BmOR3 and downstream effectors.

Authors - Jing-Yu Lin
  • KD Validated

PLoS One

Cell Survival Following Radiation Exposure Requires miR-525-3p Mediated Suppression of ARRB1 and TXN1.

Authors - Kraemer Anne A

Oncol Rep

Blue light irradiation inhibits the growth of colon cancer and activation of cancer‑associated fibroblasts.

Authors - Toshiaki Yoshimoto