Beta Arrestin 2 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 10171-1-AP

Featured Product KD/KO validated

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Con: 41 μg/150 μl

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Species specificity:
human, mouse, Xenopus

Positive WB detected in:
RAW 264.7 cells, RAW264.7 cells

Positive IP detected in:
RAW 264.7 cells

Positive IHC detected in:
human tonsil tissue, human brain tissue, human spleen tissue

Positive IF detected in:
mouse Retina tissue

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
arrestin, beta 2

Calculated molecular weight:
46 kDa

Observed molecular weight:
50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARRB2

Synonyms
ARB2, ARR2, ARRB2, Arrestin beta 2, arrestin, beta 2, BARR2, Beta arrestin 2, DKFZp686L0365
Background

Beta Arrestin 2 is a member of arrestin/beta-arrestin protein family, which are expressed at high levels in the central nervous system (CNS) and play a critical role in the regulation of G-protein coupled receptors (GPCRs) including MOR. Beta Arrestin 2 is an adaptor protein that is important for the regulation of receptors belonging to both dopaminergic and opioid systems. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.


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