ASCC1 Polyclonal antibody

ASCC1 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB,ELISA

Conjugate

Unconjugated

Cat no : 12301-1-AP

Synonyms

ASC 1 complex subunit p50, ASC1p50, ASCC1, CGI 18, RP11 150D20.4, Trip4 complex subunit p50



Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 1 publications below

Product Information

12301-1-AP targets ASCC1 in WB,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ASCC1 fusion protein Ag2946
Full Name activating signal cointegrator 1 complex subunit 1
Calculated molecular weight 45.5 kDa
Observed molecular weight 45.5 kDa
GenBank accession numberBC012291
Gene symbol ASCC1
Gene ID (NCBI) 51008
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ASCC1 (also known as p50) is a subunit of an uncharacterized complex, the activating signal co-integrator complex (ASCC). ASCC1 has been reported as regulator fo NF-kB pathway and potently inhibits the expression of NF-kB target genes. Mutations in ASCC1 in patients with Barrett esophagus (BE) have been identified as a risk factor of esophageal adenocarcinoma (EAC).

Protocols

Product Specific Protocols
WB protocol for ASCC1 antibody 12301-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Mol Cell

Translation stress and collided ribosomes are co-activators of cGAS.

Authors - Li Wan