ASTN2 Polyclonal antibody

ASTN2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 17351-1-AP

Synonyms

ASTN2, astrotactin 2, KIAA0634

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Validation Data Gallery

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  WB analysis of HepG2 using 17351-1-AP

  HepG2 cells were subjected to SDS PAGE followed by western blot with 17351-1-AP (ASTN2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HepG2 cells

Recommended dilution

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 17351-1-AP is ASTN2 Fusion Protein expressed in E. coli.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: ASTN2 fusion protein Ag11425
• Full Name: astrotactin 2
• Calculated Molecular Weight: 440 aa, 50 kDa
• Observed Molecular Weight: 148 kDa
• GenBank Accession Number: BC029272
• Gene Symbol: ASTN2
• Gene ID (NCBI): 23245
• RRID: AB_2878394
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ASTN2, also named as KIAA0634, has recently been implicated in several common disorders of the nervous system, including attention deficit hyperactivity disorder (ADHD), autism and schizophrenia. Astn2 is abundant in migrating cerebellar granule neurons when glial-guided migration is ongoing. ASTN2 forms a complex with ASTN1 that regulates the polarized trafficking of ASTN1 during migration.