Ataxin-1-Specific Polyclonal antibody

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• Ataxin-1-Specific Polyclonal antibody (20255-1-AP)

Ataxin-1-Specific Polyclonal Antibody for WB, ELISA

Cat No. 20255-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

ATXN1-Specific, ATXN1, ataxin 1, ataxin1, Ataxin-1

• 

  WB analysis using 20255-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 20255-1-AP (Ataxin-1-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: mouse brain tissue, rat brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

20255-1-AP targets Ataxin-1-Specific in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: ataxin 1
• Calculated Molecular Weight: 87 kDa
• Observed Molecular Weight: 100 kDa
• GenBank Accession Number: NM_000332
• Gene Symbol: ATXN1
• Gene ID (NCBI): 6310
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P54253
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ATXN1, also named as ATX1 and SCA1, belongs to the ATXN1 family. ATXN1 binds RNA in vitro. It may be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function. Defects in ATXN1 are the cause of spinocerebellar ataxia type 1 (SCA1) which also known as olivopontocerebellar atrophy I (OPCA I or OPCA1). The antibody is specific to ATXN1.