Mouse Angiopoietin-like 3/ANGPTL3 Recombinant monoclonal antibody, PBS Only

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• Mouse Angiopoietin-like 3/ANGPTL3 Recombinant monoclonal antibody, PBS Only (83165-3-PBS)

Angiopoietin-like 3/ANGPTL3 Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 83165-3-PBS Copied!

Clone No. 230498F11

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Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Synonyms

angiopoietin like 3, Angptl3, hypl

• 

  WB analysis using 83165-3-RR (same clone as 83165-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83165-3-RR (Angiopoietin-like 3/ANGPTL3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83165-3-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of A375 using 83165-3-RR (same clone as 83165-3-PBS)

  A375 cells were subjected to SDS PAGE followed by western blot with 83165-3-RR (Angiopoietin-like 3/ANGPTL3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83165-3-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Product Information

83165-3-PBS targets Angiopoietin-like 3/ANGPTL3 in WB, ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Fusion Protein

• Full Name: angiopoietin-like 3
• Calculated Molecular Weight: 53KD
• GenBank Accession Number: NM_013913.4
• Gene Symbol: Angptl3
• Gene ID (NCBI): 30924
• RRID: AB_3670860
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9R182
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ANGPTL3 belongs to the angiopoietin-like protein family. ANGPTL3 is mainly synthesized by liver cells and is notably expressed in kidney podocytes. Accumulating evidences have revealed that ANGPTL3 plays a critical role in both biological processes, such as lipid metabolism, angiogenesis and haematopoietic function and pathological changes, including atherosclerosis, carcinogenesis, nephrotic syndrome, diabetes, liver diseases and so on. Thus, ANGPTL3 may serve as a potential biomarker in these diseases. ANGPTL3 belongs to a multifunctional secreted protein that mainly expresses in the liver, and is regulated by numerous post-translational modifications, including multiple cleavage and glycosylation (PMID: 30615486).