AXL Recombinant antibody, PBS Only

AXL Uni-rAbTM Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 84659-1-PBS
Clone No.242014B9

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

242014B9, EC:2.7.10.1, Tyrosine-protein kinase receptor UFO, UFO

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

84659-1-PBS targets AXL in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen AXL fusion protein Eg1618 Predict reactive species
Full Name AXL receptor tyrosine kinase
Calculated Molecular Weight98kDa
Observed Molecular Weight130-140 kDa
GenBank Accession NumberNM_021913.4
Gene Symbol AXL
Gene ID (NCBI) 558
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP30530-1
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

Axl, also known as Ufo or Ark, is a receptor tyrosine kinase of the TAM (Tyro3, Axl and Mer) family. Axl is a single-pass type I membrane protein containing two fibronectin type-III domains, two Ig-like C2-type domains and one protein kinase domain. Axl mRNA is widely expressed with highest levels in the heart and skeletal muscle. Gas6 has been identified as a ligand for human Axl. Gas6/Axl signaling plays a role in cell survival, cell proliferation, migration and differentiation. It has been reported that 110-120 kDa non-glycosylated AXL protein can be detected(PMID: 31171001). Endogenous Axl is auto-phosphorylated and reacted with a tyrosine-phosphorylated protein of 140 kDa(PMID: 12730092).

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