BAK Recombinant monoclonal antibody, PBS Only

• 

  WB analysis using 85200-1-RR (same clone as 85200-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85200-1-RR (BAK antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85200-1-PBS in a different storage buffer formulation.

BAK Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 85200-1-PBS

Clone No.242458D10

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

BAK1, 242458D10, Bcl-2 homologous antagonist/killer, Bcl2-L-7, Bcl-2-like protein 7

---

Product Information

85200-1-PBS targets BAK in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: BCL2-antagonist/killer 1
• Calculated Molecular Weight: 23 kDa
• Observed Molecular Weight: 23-25 kDa
• GenBank Accession Number: BC004431
• Gene Symbol: BAK1
• Gene ID (NCBI): 578
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q16611
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

The BAK encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.