BAMBI Polyclonal antibody

BAMBI Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Publications

7

Cat no : 16100-1-AP

Synonyms

BAMBI, Non metastatic gene A protein

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Validation Data Gallery

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Recommended dilution

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 7 publications below
• IHC: See 1 publications below

Product Information

16100-1-AP targets BAMBI in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: BAMBI fusion protein Ag8974
• Full Name: BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
• Calculated Molecular Weight: 260 aa, 29 kDa
• GenBank Accession Number: BC019252
• Gene Symbol: BAMBI
• Gene ID (NCBI): 25805
• RRID: AB_10807097
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

BAMBI (BMP and activin membrane-bound inhibitor homolog) is a transmembrane protein and modulator of paracrine factors that regulate adipogenesis, including transforming growth factor (TGF) superfamily members (TGF-β and BMP) and Wnt. BAMBI is a type I TGFβ receptor antagonist and contributes to endothelial and vascular homeostasis. BAMBI deregulation has been involved in the pathogenesis of various human pathologies, such as tumor progression andmetastatic capability, pathological fibrosis and metaplastic bone formation.

Publications

Species	Application	Title
human	WB,IHC	J Cell Mol Med; Lipopolysaccharide enhances TGF-β1 signalling pathway and rat pancreatic fibrosis.; Authors - Li Sun
mouse	WB	Sci Rep; The roles of Toll-like receptor 4 in the pathogenesis of pathogen-associated biliary fibrosis caused by Clonorchis sinensis.; Authors - Chao Yan
rat	WB	Toxicology; Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway.; Authors - Shi Haitao H
mouse	WB	PLoS One; Effect of miR-20b on Apoptosis, Differentiation, the BMP Signaling Pathway and Mitochondrial Function in the P19 Cell Model of Cardiac Differentiation In Vitro.; Authors - Shasha Zhu
human	WB	J Dermatol; miR-205-5p inhibits psoriasis-associated proliferation and angiogenesis: Wnt/β-catenin and mitogen-activated protein kinase signaling pathway are involved.; Authors - Yadong Xue
human	WB	J Cancer; Exosomal miR-17-5p promotes angiogenesis in nasopharyngeal carcinoma via targeting BAMBI.; Authors - Bingyue Duan