Tested Applications
| Positive WB detected in | mouse heart tissue, rat heart tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 1 publications below |
Product Information
33437-1-AP targets BAZ2B in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | chicken |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag36147 Product name: Recombinant human BAZ2B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1833-2080 aa of NM_013450.3 Sequence: DNPLDIAVTRLADLERNIERRIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKL Predict reactive species |
| Full Name | bromodomain adjacent to zinc finger domain, 2B |
| Calculated Molecular Weight | 240kDa，2168aa |
| Observed Molecular Weight | 220-240 kDa |
| GenBank Accession Number | NM_013450.3 |
| Gene Symbol | BAZ2B |
| Gene ID (NCBI) | 29994 |
| RRID | AB_3742971 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9UIF8 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
BAZ2B(Bromodomain adjacent to zinc finger domain protein 2) is a regulatory subunit of the ATP-dependent chromatin remodeling complexes BRF1 and BRF5, which control access to DNA during DNA-templated processes. BAZ2B has been implicated in several diseases and also in unhealthy ageing. Loss of BAZ2B function has been postulated to cause neurodevelopmental disorders (PMID: 31999386, 31999386).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for BAZ2B antibody 33437-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
