Tested Applications
| Positive IHC detected in | human skin squamous cell cancer tissue, human colon cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | HeLa cells, U2OS cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:200-1:800 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
12702-1-AP targets BMPR1A in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag3410 Product name: Recombinant human BMPR1A protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 174-427 aa of BC028383 Sequence: FCYKHYCKSISSRRRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEVLDESLNKNHFQPYIM Predict reactive species |
| Full Name | bone morphogenetic protein receptor, type IA |
| Calculated Molecular Weight | 532 aa, 60 kDa |
| Observed Molecular Weight | 60-68 kDa |
| GenBank Accession Number | BC028383 |
| Gene Symbol | BMPR1A |
| Gene ID (NCBI) | 657 |
| RRID | AB_2064273 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P36894 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for BMPR1A antibody 12702-1-AP | Download protocol |
| IHC protocol for BMPR1A antibody 12702-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The 12702-1-AP BMPR1A Polyclonal antibody has 20 citations. These appear in journals including EBioMedicine, PNAS, Arterioscler Thromb Vasc Biol, ACS Appl Mater Interfaces, Cell Reports, Biomedical Pharmacotherapy, Science Signaling, International Endodontic Journal, Life Sciences, Journal of Cell Biology, Journal of Clinical and Translational Hepatology, JAHA, Frontiers in Cell and Developmental Biology, Scientific Reports, International Journal of Medical Sciences, Journal of Neuro-Oncology, Biomedical Research International, BBA, PLoS One, and bioRxiv. Research fields span preeclampsia, implantation, pulmonary hypertension, dentin regeneration, adipocyte biology, hair growth, cancer, osteogenesis, and cardiac differentiation.
| Species | Application | Title |
|---|---|---|
EBioMedicine H3K27me3-modulated Hofbauer cell BMP2 signalling enhancement compensates for shallow trophoblast invasion in preeclampsia | ||
Arterioscler Thromb Vasc Biol Binding of Hypoxia-Induced Mitogenic Factor/RELM-β to Bone Morphogenetic Protein Receptor 2 Complex Promotes Pulmonary Hypertension.
| ||
ACS Appl Mater Interfaces Valproic Acid-Loaded ZIF-8 Nanoparticles with Antibacterial, Immunomodulatory, and Dentin Regenerative Functions for Pulpitis Therapy. | ||
Cell Rep Lineage tracing reveals a shared cellular origin for supraclavicular brown and inguinal beige adipocytes. | ||
Biomed Pharmacother Pilose antler extract promotes hair growth in androgenic alopecia mice by promoting the initial anagen phase |
