BMX Polyclonal antibody, PBS Only

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• BMX Polyclonal antibody, PBS Only (27413-1-PBS)

• 

  WB analysis using 27413-1-AP (same clone as 27413-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27413-1-AP (BMX antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27413-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 27413-1-AP (same clone as 27413-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using BMX antibody (27413-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27413-1-PBS in a different storage buffer formulation.

BMX Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 27413-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

PSCTK3, PSCTK2, NTK38, ETK, EC:2.7.10.2

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Product Information

27413-1-PBS targets BMX in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag26407

  Product name: Recombinant human BMX protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 112-301 aa of BC016652

  Sequence: GNPHLLVKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVPVLKMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDFPDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGNI

• Full Name: BMX non-receptor tyrosine kinase
• Calculated Molecular Weight: 675 aa, 78 kDa
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: BC016652
• Gene Symbol: BMX
• Gene ID (NCBI): 660
• RRID: AB_3669599
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P51813
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

BMX (Bone marrow kinase on chromosome X) is a cytosolic tyrosine kinase and a member of the TEC kinase family. BMX is expressed in hematopoietic cells of the myeloid lineage where it participates in the immune response. Moreover, BMX is expressed in several types of cancers and very recently has been shown to mediate the survival and tumorigenicity of glioblastoma cancer stem cells (PMID: 22449076).