BRD7 Recombinant antibody

BRD7 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 86176-2-RR
Clone No.250776B2

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

BP75, Bromodomain-containing protein 7, CELTIX1, NAG4, Protein CELTIX 1

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inJurkat cells, mouse lung tissue, PC-3 cells, SH-SY5Y cells, COLO 320 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

86176-2-RR targets BRD7 in applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen BRD7 fusion protein Ag1461 Predict reactive species
Full Name bromodomain containing 7
Calculated Molecular Weight 651 aa, 74 kDa
Observed Molecular Weight74-78 kDa
GenBank Accession NumberBC050728
Gene Symbol BRD7
Gene ID (NCBI) 29117
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9NPI1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

BRD7 (bromodomain containing 7), is a subunit of poly-bromo-associated BRG1-associated factor (PBAF)-specific Swi/Snf chromatin remodeling complexes.BRD7 is proposed as a tumor suppressor protein, since its identification as an important component of both functional p53 and BRCA1 (breast cancer 1, early onset) pathways. BRD7 could down-regulate the GSK3beta phosphotransferase activity as dephosphorylation of GSK3B at 'Tyr-216', thus activate the Wnt signaling pathway in a DVL1-dependent manner.

Protocols

Product Specific Protocols
WB protocol for BRD7 antibody 86176-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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