|Positive WB detected in||MCF-7 cells, NCCIT cells, A549 cells, MDA-MB-231 cells, T-47D cells, PC-3 cells, BxPC-3 cells, DU 145 cells|
|Western Blot (WB)||WB : 1:5000-1:10000|
|Sample-dependent, check data in validation data gallery|
66683-1-Ig targets BTC in WB, IHC, ELISA applications and shows reactivity with Human samples.
|Host / Isotype||Mouse / IgG1|
|Immunogen||BTC fusion protein Ag26724|
|Calculated molecular weight||20 kDa|
|Observed molecular weight||20 kDa|
|GenBank accession number||BC011618|
|Gene ID (NCBI)||685|
|Purification Method||Protein G purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, binds and activates ErbB1 and ErbB4 homodimers. BTC is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. BTC was expressed in tumors and involved in tumor growth progression.