Beta Arrestin 2 Recombinant antibody, PBS Only

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  WB analysis using 82780-6-RR (same clone as 82780-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82780-6-RR (Beta Arrestin 2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82780-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 82780-6-PBS

  Biolayer interferometry (BLl) kinetic assay of 82780-6-PBS against Human Beta Arrestin 2 was performed. The affinity constant is below 1 pM.

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  Affinity and Kinetic Characterization of 82780-6-RR

  Biolayer interferometry (BLl) kinetic assays of 82780-6-RR against Human Beta Arrestin 2 were performed. The affinity constant is below 1 pM.

Beta Arrestin 2 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 82780-6-PBS

Clone No.241470F8

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

ARRB2, β-Arrestin 2, 241470F8, ARB2, ARR2

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Product Information

82780-6-PBS targets Beta Arrestin 2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Beta Arrestin 2 fusion protein Ag0227
• Full Name: arrestin, beta 2
• Calculated Molecular Weight: 46 kDa
• Observed Molecular Weight: 47-50 kDa
• GenBank Accession Number: BC007427
• Gene Symbol: Beta Arrestin 2
• Gene ID (NCBI): 409
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P32121
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Beta Arrestin 2 is a member of arrestin/beta-arrestin protein family, which are expressed at high levels in the central nervous system (CNS) and play a critical role in the regulation of G-protein coupled receptors (GPCRs) including MOR. Beta Arrestin 2 is an adaptor protein that is important for the regulation of receptors belonging to both dopaminergic and opioid systems. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.