TBXT Polyclonal antibody

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• TBXT Polyclonal antibody (20741-1-AP)

TBXT Polyclonal Antibody for WB, ELISA

Cat No. 20741-1-AP Copied!

Publications (1)

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IF, ELISA

Synonyms

Brachyury protein, Brachyury T, Brachyury-T, Protein T, T, brachyury homolog (mouse), T-box transcription factor T, TBXT, TFT

• 

  WB analysis of mouse liver using 20741-1-AP

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 20741-1-AP (Brachyury-T antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of mouse liver using 20741-1-AP

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 20741-1-AP (Brachyury-T antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: mouse liver tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

20741-1-AP targets TBXT in WB, IF, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: T, brachyury homolog (mouse)
• Calculated Molecular Weight: 47 kDa
• Observed Molecular Weight: 44 kDa
• GenBank Accession Number: NM_003181
• Gene Symbol: TBXT
• Gene ID (NCBI): 6862
• RRID: AB_2878730
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O15178
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Brachyury T is involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. It binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. Genetic variations in T are associated with susceptibility to neural tube defects (NTD). The antibody is specific to Brachyury T.

Publications

What published studies show

The TBXT (Brachyury T) polyclonal antibody (Cat# 20741-1-AP) has 1 total citation. It appears in Journal of Neurochemistry (IF 4.6), published in 2026. The cited study investigates how a TFG p.G269V mutation disrupts motor neuron function in iPSC-derived models through Wnt signaling dysregulation, placing this antibody's use in the fields of neurochemistry, stem cell biology, and developmental signaling pathways. The application used was immunofluorescence (IF) in human samples.

Automatically generated from the 1 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	IF	J Neurochem; TFG p.G269V Mutation Disrupts Motor Neuron Function in iPSC-Derived Models via Wnt Signaling Dysregulation.; Authors - Zhiqiang Mu