C10orf76 Polyclonal antibody, PBS Only

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• C10orf76 Polyclonal antibody, PBS Only (33627-1-PBS)

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  WB analysis using 33627-1-AP (same clone as 33627-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 33627-1-AP (C10orf76 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33627-1-PBS in a different storage buffer formulation.

C10orf76 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 33627-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

Armadillo-like helical domain-containing protein 3, ARMH3

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Product Information

33627-1-PBS targets C10orf76 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag38164

  Product name: Recombinant human C10orf76 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 539-689 aa of NM_024541.2

  Sequence: DTFLPTPSSYDELYYEIIRMHQSFDNLYSMVLRLSTNAGQWKEAASKVTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQDGLDQYERYSEQHKEAAFFKELVRSISTNVRRNLAFHTLSQEVLLKEFSTIS

• Full Name: chromosome 10 open reading frame 76
• Calculated Molecular Weight: 79kDa，689aa
• Observed Molecular Weight: 70-79 kDa
• GenBank Accession Number: NM_024541.2
• Gene Symbol: C10orf76
• Gene ID (NCBI): 79591
• RRID: AB_3743033
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q5T2E6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

C10orf76, also known as ARMH3 (Armadillo-like helical domain-containing protein 3), was previously reported to be a regulator of phosphatidylinositol 4-kinase beta (PI4KB, also known as PI4KIIIbeta) at the TGN. Upon cGAMP-triggered translocation, ARMH3 interacted with STING at the Golgi and recruited phosphatidylinositol 4-kinase beta (PI4KB) to synthesize PI4P, which directed STING Golgi-to-endosome trafficking via PI4P-binding proteins AP-1 and GGA2 (PMID: 39580461, 36921576).