|Positive WB detected in||mouse lung tissue, rat lung tissue|
|Positive IHC detected in||human colon cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:500-1:2000|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
13931-1-AP targets CA4 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||CA4 fusion protein Ag4960|
|Full Name||carbonic anhydrase IV|
|Calculated molecular weight||35 kDa|
|Observed molecular weight||35 kDa|
|GenBank accession number||BC057792|
|Gene ID (NCBI)||762|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
CA4(Carbonic anhydrase 4) is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressing on the luminal surfaces of pulmonary, chorionic (and certain other) capillaries and of proximal renal tubules. It plays a critical role by maintaining the pH in the outer retina, which is important for the normal function of photoreceptors. This protein belongs to the alpha-carbonic anhydrase family.
Carbonic anhydrase IV in lizard chemical signals
Down-regulated C4orf19 confers poor prognosis in colon adenocarcinoma identified by gene co-expression network.
A CCL2+DPP4+ subset of mesenchymal stem cells expedites aberrant formation of creeping fat in humans