CACNG2 Polyclonal antibody

CACNG2 Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC,ELISA

Conjugate

Unconjugated

Cat no : 20969-1-AP

Synonyms

CACNG2, stargazin, TARP gamma-2

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Validation Data Gallery

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  IHC staining of mouse brain using 20969-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20969-1-AP (CACNG2 Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of mouse brain using 20969-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20969-1-AP (CACNG2 Antibody) at dilution of 1:50 (under 40x lens).

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Tested Applications

• Positive IHC detected in: mouse brain tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

20969-1-AP targets CACNG2 in IHC,ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: calcium channel, voltage-dependent, gamma subunit 2
• Calculated Molecular Weight: 36 kDa
• GenBank Accession Number: NM_006078
• Gene Symbol: CACNG2
• Gene ID (NCBI): 10369
• RRID: AB_2878778
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Voltage-dependent calcium channel gamma-2 subunit (CACNG2, also known as stargazin or TARP gamma-2) is a brain-specific transmembrane AMPA receptor regulatory proteint. CACNG2 is intimately involved in the trafficking of glutamatergic AMPA receptors and the modulation of their ion channel function (PMID: 20688780).