CaMKII Delta Polyclonal antibody

CaMKII Delta Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Publications

5

Cat no : 15443-1-AP

Synonyms

CaM kinase II subunit delta, CaMK II subunit delta, CAMK2D, CAMKD, CaMKII delta

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Validation Data Gallery

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Published Applications

• WB: See 5 publications below
• IF: See 1 publications below

Product Information

15443-1-AP targets CaMKII Delta in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: CaMKII Delta fusion protein Ag7323
• Full Name: calcium/calmodulin-dependent protein kinase II delta
• Calculated Molecular Weight: 59 kDa
• Observed Molecular Weight: 64 kDa
• GenBank Accession Number: BC032784
• Gene Symbol: CAMK2D
• Gene ID (NCBI): 817
• RRID: AB_2068087
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CaMKII delta, also named as CAMKD and CaMKII delta, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and CaMK subfamily. CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release, composed of four different chains: alpha, beta, gamma, and delta. The CAMK2 protein kinases contain a unique C-terminal subunit association domain responsible for oligomerization. The different chains assemble into homo-or heteromultimeric holoenzymes composed of 8 to 12 subunits. This antibody may have cross reaction with CAMK2A/B/G due to the high homology.

Publications

Species	Application	Title
mouse	WB	Cell Calcium; Activation of transient receptor potential vanilloid 4 exacerbates myocardial ischemia-reperfusion injury via JNK-CaMKII phosphorylation pathway in isolated mice hearts.; Authors - Shaoshao Zhang
mouse	WB	J Cell Physiol; PMID: 30488495; Authors - Jiali Nie
rat	WB	Life Sci; Chronic stimulation of the sigma-1 receptor ameliorates ventricular ionic and structural remodeling in a rodent model of depression.; Authors - Xiuhuan Chen
rat	WB	Mol Cell Biochem; Pleiotropic, non-cell death-associated effects of inhibitors of receptor-interacting protein kinase 1 in the heart.; Authors - C Horvath
mouse	WB,IF	JCI Insight; Oxidized CaMKII promotes asthma through the activation of mast cells.; Authors - Jingjing Qu