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  • KD/KO Validated

CBX1 Polyclonal antibody

CBX1 Polyclonal Antibody for WB, IP, IF, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 10241-2-AP


CBX, CBX1, Chromobox protein homolog 1, Heterochromatin protein p25, HP1 BETA, HP1Hs beta, HP1Hsbeta, M31, MOD1, Modifier 1 protein, p25beta

Tested Applications

Positive WB detected inA431 cells, MCF-7 cells, HEK-293 cells, human brain tissue, NIH/3T3 cells
Positive IP detected inHEK-293 cells
Positive IHC detected inhuman stomach cancer tissue, mouse testis tissue, human colon cancer tissue, human lung cancer tissue, human ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHEK-293 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:250-1:1000
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10241-2-AP targets CBX1 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CBX1 fusion protein Ag0328
Full Name chromobox homolog 1 (HP1 beta homolog Drosophila )
Calculated Molecular Weight 27 kDa
Observed Molecular Weight 27 kDa
GenBank Accession NumberBC002609
Gene Symbol CBX1
Gene ID (NCBI) 10951
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

One function of heterochromatin is the epigenetic silencing by sequestration of genes into transcriptionally repressed nuclear neighborhoods. Heterochromatin protein 1 (HP1) is a major component of heterochromatin and is a candidate for establishing and mediating gene silencing. This protein is expressed in all adult and embryonic tissues, as a homodimer.


Product Specific Protocols
WB protocol for CBX1 antibody 10241-2-APDownload protocol
IHC protocol for CBX1 antibody 10241-2-APDownload protocol
IF protocol for CBX1 antibody 10241-2-APDownload protocol
IP protocol for CBX1 antibody 10241-2-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



J Exp Med

ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.

Authors - Longfei Ma

Nat Commun

The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction.

Authors - Guang Yang

J Cell Biol

Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins.

Authors - Jiang Wei-Qin WQ
  • KD Validated

J Virol

PIWIL4 Maintains HIV-1 Latency by Enforcing Epigenetically Suppressive Modifications on the 5' Long Terminal Repeat.

Authors - Zhangping He

Front Genet

Identification and Validation of Chromobox Family Members as Potential Prognostic Biomarkers and Therapeutic Targets for Human Esophageal Cancer.

Authors - Xuefen Fang

Adv Sci (Weinh)

N6 -Methyladenosine-Modified CBX1 Regulates Nasopharyngeal Carcinoma Progression Through Heterochromatin Formation and STAT1 Activation

Authors - Yin Zhao


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


WEI (Verified Customer) (03-08-2022)

Band at predicted size

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:1000
  • Cell Tissue Type: Mouse Heart