CC2D2A Polyclonal antibody, PBS Only

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• CC2D2A Polyclonal antibody, PBS Only (22293-1-PBS)

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  WB analysis using 22293-1-AP (same clone as 22293-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22293-1-AP (CC2D2A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 22293-1-AP (same clone as 22293-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer slide using 22293-1-AP (CC2D2A Antibody) at dilution of 1:50(under 10x lens). This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 22293-1-AP (same clone as 22293-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer slide using 22293-1-AP (CC2D2A Antibody) at dilution of 1:50(under 40x lens). This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

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  IF Staining of hTERT-RPE1 cells using 22293-1-AP (same clone as 22293-1-PBS)

  IF result (strong nucleus and the base stain) of anti-CC2D2A (22293-1-AP, 1:50) with serum-starved hTERT-RPE1 (MeOH fixed) by Dr. Moshe Kim. This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

CC2D2A Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Cat No. 22293-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Synonyms

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Product Information

22293-1-PBS targets CC2D2A in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: coiled-coil and C2 domain containing 2A
• Calculated Molecular Weight: 186 kDa
• Observed Molecular Weight: 190 kDa
• GenBank Accession Number: NM_020785
• Gene Symbol: CC2D2A
• Gene ID (NCBI): 57545
• RRID: AB_2879063
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9P2K1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CC2D2A, also named as KIAA1345, may be involved in cilia formation. CC2D2A encodes a protein with similar overall structure to RPGRIP1L, including coiled-coil domains, a C2 domain, and an overlapping centrosomal protein-related domain. CC2D2A physically interacts with CEP290, and loss of Cc2d2a function in the zebrafish sentinel mutant results in abnormal body shape and pronephric (kidney) cysts that is strongly exacerbated by knockdown of Cep290 function. (PMID:19778711 )Defects in CC2D2A are the cause of Meckel syndrome type 6 (MKS6). Defects in CC2D2A are the cause of Joubert syndrome type 9 (JBTS9). The antibody is specific to CC2D2A.