Product Information
33150-1-PBS targets CCNB1IP1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
| Tested Reactivity | human, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag38148 Product name: Recombinant human CCNB1IP1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-277 aa of BC004435 Sequence: MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLDIVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAEGHLKQMEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDSLRLRNITIANHEGTLEPSMIAQSGVLGFPLGNNSKFPLDNTPVRNRGDGDGDFQFRPFFAGSPTAPEPSNSFFSFVSPSRELEQQQVSSRAFKVKRI Predict reactive species |
| Full Name | cyclin B1 interacting protein 1 |
| Calculated Molecular Weight | 32 kDa |
| Observed Molecular Weight | 32 kDa |
| GenBank Accession Number | BC004435 |
| Gene Symbol | CCNB1IP1 |
| Gene ID (NCBI) | 57820 |
| RRID | AB_3742873 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9NPC3 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Cyclin-B1-interacting protein 1 (CCNB1IP1) is an interacting protein of cyclin B1 involved in regulating cell cycle progression, and may be implicated in tumour events (PMID: 12612082). CCNB1IP1 modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Its overexpression causes delayed entry into mitosis (PMID: 12612082; 17297447). Additionally, CCNB1IP1 has been shown to stabilize the MYCN protein, which is a critical factor in neuroblastoma tumorigenesis (PMID: 37461251).
