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  • KD/KO Validated

Cyclin D2 Polyclonal antibody

Cyclin D2 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse and More (3)





Cat no : 10934-1-AP


CCND2, cyclin D, cyclin D2, G1/S-specific cyclin-D2

Tested Applications

Positive WB detected inCaco-2 cells, MCF-7 cells, NIH/3T3 cells, U2OS cells, HEK-293 cells
Positive IHC detected inhuman renal cell carcinoma tissue, human gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:250-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

10934-1-AP targets Cyclin D2 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, goat, pig, bovine
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Cyclin D2 fusion protein Ag1377
Full Name cyclin D2
Calculated molecular weight 32 kDa
Observed molecular weight 34 kDa
GenBank accession numberBC010958
Gene symbol CCND2
Gene ID (NCBI) 894
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CCND2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. CCND2 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of CCND2 was observed in ovarian and testicular tumors.


Product Specific Protocols
WB protocol for Cyclin D2 antibody 10934-1-APDownload protocol
IHC protocol for Cyclin D2 antibody 10934-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




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