CCR6 Monoclonal antibody

CCR6 Monoclonal Antibody for IHC,ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

IHC,ELISA

Conjugate

Unconjugated

CloneNo.

1C11A9

Cat no : 66801-1-Ig

Synonyms

BN 1, C C chemokine receptor type 6, C C CKR 6, CC CKR 6, CCR 6, CCR6, CD196, Chemokine receptor like 3, CKR L3, CKR6, CKRL3, CMKBR6, DCR2, DRY 6, DRY6, G protein coupled receptor 29, GPR CY4, GPR29, GPRCY4, LARC receptor, STRL22



Tested Applications

Positive IHC detected inhuman tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IF experiment? We recommend our CoraLite®594 conjugated versions of this antibody.

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:250-1:1000
Sample-dependent, check data in validation data gallery

Product Information

66801-1-Ig targets CCR6 in IHC,ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen CCR6 fusion protein Ag24195
Full Name chemokine (C-C motif) receptor 6
Calculated molecular weight 42 kDa
GenBank accession numberBC037960
Gene symbol CCR6
Gene ID (NCBI) 1235
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CCR6, the gene encoding chemokine (C-C motif) receptor 6, that was a specific marker for Th17 cells, distinguishing them from other helper T-cells. Although CCR6 also expressed in IL-17-producing γδ T cells as well as in subsets of B cells and dendritic cells (PMID: 19830744 ). CCR6 polymorphism was associated with rheumatoid arthritis susceptibility (PMID: 20453841). CD196 is involved in host defense and inflammation at epithelial sites and in IL-17-driven autoimmunity in human diseases.

Protocols

Product Specific Protocols
IHC protocol for CCR6 antibody 66801-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols