CCR7 Polyclonal antibody

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• CCR7 Polyclonal antibody (55425-1-AP)

CCR7 Polyclonal Antibody for IHC, ELISA

Cat No. 55425-1-AP Copied!

Publications (3)

Download datasheet

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

IHC, ELISA

Synonyms

BLR2, C C chemokine receptor type 7, C C CKR 7, C-C chemokine receptor type 7, CC CKR 7

• 

  IHC staining of human tonsillitis using 55425-1-AP

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 55425-1-AP (CCR7 Antibody) at dilution of 1:50 (under 10x lens).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of human tonsillitis using 55425-1-AP

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 55425-1-AP (CCR7 Antibody) at dilution of 1:50 (under 40x lens).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive IHC detected in: human tonsillitis tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

55425-1-AP targets CCR7 in IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: chemokine (C-C motif) receptor 7
• Calculated Molecular Weight: 43 kDa
• GenBank Accession Number: NM_001838
• Gene Symbol: CCR7
• Gene ID (NCBI): 1236
• RRID: AB_2881325
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P32248
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

C-C chemokine receptor type 7 (CCR7) , which belongs to the G-protein coupled receptor 1 family, is also a receptor for the MIP-3-beta chemokine, and probablely acts as mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. CCR7 is specially expressed in various lymphoid tissues and activated B- and T-lymphocytes, and can be strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.

Publications

What published studies show

The CCR7 polyclonal antibody (Cat# 55425-1-AP) has 3 citations. These appear in Nature Communications, Advanced Science, and Clinical, Cosmetic and Investigational Dermatology. The associated research fields include hepatocellular carcinoma, tenogenic differentiation of mesenchymal stem cells, and abdominal aortic aneurysm risk prediction in psoriasis patients. All citations used the IHC application.

Automatically generated from the 3 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	IHC	Nat Commun; A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma.; Authors - Yiming Lu
rat	IHC	Adv Sci (Weinh); Material Stiffness in Cooperation with Macrophage Paracrine Signals Determines the Tenogenic Differentiation of Mesenchymal Stem Cells; Authors - Renwang Sheng
human	IHC	Clin Cosmet Investig Dermatol; Identification of a Gene Expression Signature to Predict the Risk of Abdominal Aortic Aneurysm in Psoriasis Patients; Authors - Xintong Lyu