Anti-Mouse CD105 (MJ7/18)

CD105 Monoclonal Antibody for FC, IF

Host / Isotype

Rat / IgG2a, kappa

Reactivity

Mouse

Applications

IF, FC

Conjugate

Unconjugated

CloneNo.

MJ7/18

Cat no : 65048-1-Ig

Synonyms

AI528660, AI662476, CD105, endoglin, Eng, S endoglin



Tested Applications

Positive IF detected inmouse liver tissue
Positive FC detected inbEnd.3 cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:200-1:800
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

65048-1-Ig targets CD105 in IF, FC applications and shows reactivity with Mouse samples.

Tested Reactivity Mouse
Host / Isotype Rat / IgG2a, kappa
Class Monoclonal
Type Antibody
Immunogen Inflamed mouse skin
Full Name endoglin
GenBank accession numberBC029080
Gene symbol Eng
Gene ID (NCBI) 13805
Conjugate Unconjugated
Form Liquid
Purification Method Affinity purification
Storage Buffer Borate buffered saline, pH 8.2.
Storage ConditionsStore at 2-8°C. Stable for one year after shipment.

Background Information

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)

Protocols

Product Specific Protocols
IF protocol for CD105 antibody 65048-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols