Anti-Mouse CD105 (MJ7/18)
CD105 Monoclonal Antibody for FC, IF
Host / Isotype
Rat / IgG2a, kappa
Reactivity
Mouse
Applications
IF, FC
Conjugate
Unconjugated
CloneNo.
MJ7/18
Cat no : 65048-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive IF detected in | mouse liver tissue |
Positive FC detected in | bEnd.3 cells |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF) | IF : 1:200-1:800 |
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Product Information
65048-1-Ig targets CD105 in IF, FC applications and shows reactivity with Mouse samples.
Tested Reactivity | Mouse |
Host / Isotype | Rat / IgG2a, kappa |
Class | Monoclonal |
Type | Antibody |
Immunogen | Inflamed mouse skin |
Full Name | endoglin |
GenBank accession number | BC029080 |
Gene symbol | Eng |
Gene ID (NCBI) | 13805 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Affinity purification |
Storage Buffer | Borate buffered saline, pH 8.2. |
Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
Background Information
Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)
Protocols
Product Specific Protocols | |
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IF protocol for CD105 antibody 65048-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |