Anti-Mouse Endoglin/CD105 (MJ7/18)

Endoglin/CD105 Monoclonal Antibody for IF-P, FC

Host / Isotype

Rat / IgG2a, kappa

Reactivity

mouse

Applications

IF-P, FC

Conjugate

Unconjugated

CloneNo.

MJ7/18

Cat no : 65048-1-Ig

Synonyms

CD105, S endoglin, MJ7/18, Eng, endoglin



Tested Applications

Positive IF-P detected inmouse liver tissue
Positive FC detected inbEnd.3 cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:200-1:800
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

65048-1-Ig targets Endoglin/CD105 in IF-P, FC applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Host / Isotype Rat / IgG2a, kappa
Class Monoclonal
Type Antibody
Immunogen Inflamed mouse skin
Full Name endoglin
GenBank Accession NumberBC029080
Gene Symbol CD105
Gene ID (NCBI) 13805
RRIDAB_2918360
Conjugate Unconjugated
Form Liquid
Purification MethodAffinity purification
Storage Buffer Borate buffered saline, pH 8.2.
Storage ConditionsStore at 2-8°C. Stable for one year after shipment.

Background Information

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)

Protocols

Product Specific Protocols
IF protocol for Endoglin/CD105 antibody 65048-1-IgDownload protocol
FC protocol for Endoglin/CD105 antibody 65048-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols