CoraLite® Plus 488 Anti-Mouse CD11b (M1/70)

CD11b Monoclonal Antibody for IF, FC

Host / Isotype

Rat / IgG2b, kappa


Mouse, Human and More (2)




CoraLite® Plus 488 Fluorescent Dye



Cat no : CL488-65055


Cd11b, CD11b/CD18, CR3, CR3A, F730045J24Rik, integrin alpha M, Itgam, Ly 40, Mac 1, Mac 1a, MAC1

Tested Applications

Positive IF detected inmouse splenocytes
Positive FC detected inmouse bone marrow cells

Recommended dilution

Immunofluorescence (IF)IF : 1:200-1:800
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-65055 targets CD11b in IF, FC applications and shows reactivity with Mouse, Human samples.

Tested Reactivity Mouse, Human
Cited Reactivitymouse, rat
Host / Isotype Rat / IgG2b, kappa
Class Monoclonal
Type Antibody
Immunogen C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes
Full Name integrin alpha M
GenBank Accession NumberBC156991
Gene Symbol Itgam
Gene ID (NCBI) 16409
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAffinity purification
Storage Buffer PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).


Product Specific Protocols
IF protocol for CL Plus 488 CD11b antibody CL488-65055Download protocol
FC protocol for CL Plus 488 CD11b antibody CL488-65055Download protocol
Standard Protocols
Click here to view our Standard Protocols



Vet Res

Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis

Authors - Luqiu Feng

Biomed Pharmacother

Mitochondrion-NLRP3 inflammasome activation in macrophages: A novel mechanism of the anti-inflammatory effect of Notopterygium in rheumatoid arthritis treatment

Authors - Xiangxiang Liu