CD134/OX40 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 84247-4-RR (same clone as 84247-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84247-4-RR (OX40/TNFRSF4 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84247-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84247-4-RR

  Biolayer interferometry (BLl) kinetic assays of 84247-4-RR against Human CD134/OX40 were performed. The affinity constant is 5.21 nM.

CD134/OX40 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 84247-4-PBS

Clone No.241398B4

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

TNFRSF4, OX40L receptor, OX40, CD134, ACT35 antigen

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Product Information

84247-4-PBS targets CD134/OX40 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Fusion Protein

• Full Name: tumor necrosis factor receptor superfamily, member 4
• Calculated Molecular Weight: 29 kDa
• Observed Molecular Weight: 45-50 kDa
• GenBank Accession Number: NM_003327
• Gene Symbol: CD134
• Gene ID (NCBI): 7293
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P43489
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CD134 (OX40) is a member of the TNFR-superfamily of receptors. Predominantly expressed on activated T cells, CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule. CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmunity (PMID: 26215166). CD134 can interact with TRAF2, TRAF3, and TRAF5.