CD16 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 16559-1-AP

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human placenta tissue

Positive IHC detected in:
human liver tissue, human tonsillitis tissue

Positive FC detected in:
U-937 cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

Calculated molecular weight:
254aa,29 kDa

Observed molecular weight:
55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FCGR3A

Synonyms
CD16, CD16A, CD16a antigen, Fc gamma RIII, Fc gamma RIII alpha, Fc gamma RIIIa, FCG3, FCGR3, FCGR3A, FCGRIII, FCR 10, FCRIII, FCRIIIA, IGFR3, IgG Fc receptor III 2
Background

CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B.


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