Anti-Human CD18 (TS1/18)

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• Anti-Human CD18 (TS1/18) (65190-1-Ig)

CD18 Monoclonal Antibody for FC

Cat No. 65190-1-Ig Copied!

Clone No. TS1/18

Publications (1)

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Host / Isotype

Mouse / IgG1, kappa

Reactivity

human

Applications

FC

Synonyms

ITGB2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Integrin beta 2, Integrin beta-2, LAD

• 

  FC experiment of human PBMCs using 65190-1-Ig

  1X10^6 human PBMCs were surface stained with 0.2 ug Anti-Human CD18 (65190-1-Ig, Clone:TS1/18) and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (red), or CoraLite®488-Conjugated Mouse IgG1 Isotype Control. Cells were not fixed. Lymphocytes were gated.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  FC experiment of human PBMCs using 65190-1-Ig

  1X10^6 human PBMCs were surface stained with 0.2 ug Anti-Human CD18 (65190-1-Ig, Clone:TS1/18) and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) at dilution 1:1000, or CoraLite®488-Conjugated Mouse IgG1 Isotype Control. Cells were not fixed. Lymphocytes were gated.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive FC detected in: human PBMCs

Recommended dilution

• Flow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

65190-1-Ig targets CD18 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG1, kappa
• Class: Monoclonal
• Type: Antibody
• Immunogen:

  Human Beta 2 Integrin

• Full Name: integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
• Calculated Molecular Weight: 85 kDa
• GenBank Accession Number: BC005861
• Gene Symbol: CD18
• Gene ID (NCBI): 3689
• ENSEMBL Gene ID: ENSG00000160255
• RRID: AB_2918460
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P05107
• Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
• Storage Conditions: Store at 2-8°C. Stable for one year after shipment.

Background Information

CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570).

Publications

What published studies show

The Anti-Human CD18 (TS1/18) monoclonal antibody (Cat# 65190-1-Ig) has 1 citation. It appears in Scientific Reports (2025), where it was used by flow cytometry to study the constitutive interaction between neutrophils and von Willebrand factor in peripheral blood. The research falls within hematology and immunology, focusing on leukocyte adhesion and platelet–neutrophil interactions.

Automatically generated from the 1 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
	FC	Sci Rep; Constitutive interaction between neutrophils and von Willebrand factor in peripheral blood; Authors - Yan Wan