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CD1a Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17325-1-AP

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Con: 47 μg/150 μl

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Tested Applications

Applications:
WB, ELISA
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CD1a Antibody WB K-562 cells 17325-1-AP

K-562 cells were subjected to SDS PAGE followed by western blot with 17325-1-AP (CD1a antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours

Species specificity:
human, mouse
Positive WB detected in:
K-562 cells, Jurkat cells, mouse liver tissue, mouse skin tissue, mouse thymus tissue, Raji cells
Recommended dilution:
WB : 1:500-1:1000
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
CD1a fusion protein Ag11304
Full name:
CD1a molecule
Calculated molecular weight:
327aa,37 kDa
Observed molecular weight:
65-70 kDa
GenBank accession number:
BC031645
Gene ID (NCBI):
909
Gene symbol
CD1A
Synonyms
CD1, CD1A, CD1a molecule, FCB6, HTA1, hTa1 thymocyte antigen, R4, T6

Background

CD1a is an antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to the cell surface. CD1a is a 50-kDa glycoprotein. It has a heterodimer form with molecular weight of 65-70 kDa.


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