CD244 Polyclonal antibody

CD244 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG


human and More (1)





Cat no : 16677-1-AP


2B4, CD244, h2B4, NAIL, NKR2B4, SLAMF4

Tested Applications

Positive WB detected inNK-92 cells

Recommended dilution

Western Blot (WB)WB : 1:1000-1:8000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

16677-1-AP targets CD244 in WB, IF, IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, pig
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CD244 fusion protein Ag9860
Full Name CD244 molecule, natural killer cell receptor 2B4
Calculated Molecular Weight 365 aa, 41 kDa
Observed Molecular Weight60-70 kDa
GenBank Accession NumberBC053985
Gene Symbol CD244
Gene ID (NCBI) 51744
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CD244, also known as SLAMF4 or 2B4, is a type I transmembrane glycoprotein belonging to the signaling lymphocyte activation molecule (SLAM) family. It consists of an extracellular segment with two immunoglobulin (Ig)-like domains, a transmembrane region, and a cytoplasmic domain containing tyrosine-based motifs (PMID: 9841922; 30546369). CD244 is present on natural killer (NK) cells, γδ T cells, a subset of CD8+ T cells, monocytes, basophils, dendritic cells, and myeloid-derived suppressor cells (MDSCs) (PMID: 30546369). It binds to CD48 with high affinity and transmits stimulatory or inhibitory signals that regulate immune function (PMID: 9841922; 18523281).


Product Specific Protocols
WB protocol for CD244 antibody 16677-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



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