|Positive FC detected in||human peripheral blood lymphocytes|
|This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.|
|Sample-dependent, check data in validation data gallery|
65191-1-Ig targets CD29 in applications and shows reactivity with Human samples.
|Host / Isotype||Mouse / Mouse IgG1, kappa|
|Full Name||integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)|
|Calculated molecular weight||88 kDa|
|GenBank accession number||BC020057|
|Gene ID (NCBI)||3688|
|Purification Method||Protein A purification|
|Storage Buffer||PBS with 0.1% sodium azide, pH 7.3.|
|Storage Conditions||Store at 2-8°C.|
Integrin beta-1 (ITGB1), also named as CD29, is a 130 kDa single chain type I glycoprotein that is expressed in a heterodimeric complex with one of six distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. It is one of the essential surface molecules expressed on human MSC from bone marrow and other sources. The β1 subunit is also broadly expressed on lymphocytes and monocytes, weakly expressed on granulocytes, and not expressed on erythrocytes. These receptors are involved in a variety of cell-cell and cell-matrix interactions.