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Anti-Human CD300a Rabbit Recombinant Antibody, PBS Only (98268-1-PBS)

Anti-Human CD300a Rabbit Recombinant Antibody, PBS Only

Name: Anti-Human CD300a Rabbit Recombinant Antibody, PBS Only, 1mg
Brand: Proteintech
SKU: 98268-1-PBS-1MG

CD300a Uni-rAb^® Recombinant Antibody for FC

Cat No. 98268-1-PBS

Clone No. 242131H4

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

242131H4, CD300 antigen-like family member A, CD300a molecule, CLM 8, CLM-8

Formulation: PBS Only

PBS, Azide

PBS Only

Conjugate: Unconjugated

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FC experiment of human peripheral blood leukocytes using 98268-1-RR (same clone as 98268-1-PBS)
1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD300a Rabbit Recombinant Antibody (98268-1-RR, Clone: 242131H4) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98268-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
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1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD300a Rabbit Recombinant Antibody (98268-1-RR, Clone: 242131H4) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98268-1-PBS in a different storage buffer formulation.
Affinity and Kinetic Characterization of 98268-1-RR
Biolayer interferometry (BLl) kinetic assays of 98268-1-RR against Human CD300a were performed. The affinity constant is below 1 pM.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Overview

Tested Applications
Product Information

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Product Information

98268-1-PBS targets CD300a in FC applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	CatNo: Eg2652 Product name: Recombinant Human CD300A protein (rFc Tag) Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 18-178 aa of NM_007261.4 Sequence: LSKCRTVAGPVGGSLSVQCPYEKEHRTLNKYWCRPPQIFLCDKIVETKGSAGKRNGRVSIRDSPANLSFTVTLENLTEEDAGTYWCGVDTPWLRDFHDPVVEVEVSVFPASTSMTPASITAAKTSTITTAFPPVSSTTLFAVGATHSASIQEETEEVVNSQ Predict reactive species
Full Name	CD300a molecule
Calculated Molecular Weight	33 kDa
GenBank Accession Number	NM_007261.4
Gene Symbol	CD300a
Gene ID (NCBI)	11314
RRID	AB_3745934
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	Q9UGN4-1
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

Human CD300a is a transmembrane protein, with an immunoglobulin (Ig)V-like extracellular domain and a cytoplasmic tail containing immunoreceptor tyrosine-based inhibitory motifs (ITIMs), providing the receptor with an inhibitory capacity. The relevance of the CD300a molecule in several pathological conditions has been highlighted by multiple studies. (PMID: 37762055)