FITC Anti-Mouse CD31 (390)

CD31 Monoclonal Antibody for FC

Host / Isotype

Rat / IgG2a

Reactivity

Mouse and More (1)

Applications

FC

Conjugate

FITC Fluorescent Dye

CloneNo.

390

Cat no : FITC-65058

Synonyms

C85791, Cd31, Pecam, PECAM 1, Pecam1



Tested Applications

Positive FC detected inmouse splenocytes

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Published Applications

FCSee 1 publications below

Product Information

FITC-65058 targets CD31 in FC applications and shows reactivity with Mouse samples.

Tested Reactivity Mouse
Cited Reactivity rat
Host / Isotype Rat / IgG2a
Class Monoclonal
Type Antibody
Immunogen C3H/HeJ mouse hematopoietic progenitor cell line 32D
Full Name platelet/endothelial cell adhesion molecule 1
GenBank accession numberBC008519
Gene symbol Pecam1
Gene ID (NCBI) 18613
Conjugate FITC Fluorescent Dye
Excitation/Emission maxima wavelengths494 nm/520 nm
Form Liquid
Purification Method Affinity purification
Storage Buffer PBS with 0.1% sodium azide.
Storage ConditionsStore at 2-8°C. Avoid exposure to light.

Background Information

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).

Protocols

Product Specific Protocols
FC protocol for FITC CD31 antibody FITC-65058Download protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratFC

J Cell Mol Med

Osthole stimulates bone formation, drives vascularization and retards adipogenesis to alleviate alcohol-induced osteonecrosis of the femoral head.

Authors - Hongping Yu