Mouse CD38 Recombinant monoclonal antibody, PBS Only

• 

  WB analysis using 85843-1-RR (same clone as 85843-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85843-1-RR (Cd38 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85843-1-PBS in a different storage buffer formulation.

CD38 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 85843-1-PBS

Clone No.250107D9

Host / Isotype

Rabbit / IgG

Reactivity

mouse, rat

Applications

WB, Indirect ELISA

Synonyms

ADP ribosyl cyclase/cyclic ADP ribose hydrolase, CD38 antigen, Cyclic ADP ribose hydrolase 1

---

Product Information

85843-1-PBS targets CD38 in WB, Indirect ELISA applications and shows reactivity with mouse, rat samples.

• Tested Reactivity: mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg2915

  Product name: Recombinant Mouse CD38 protein (rFc Tag)

  Source: mammalian cells-derived, V37

  Tag: C-rFc

  Domain: 45-304 aa of NM_007646.5

  Sequence: LRPRSLLVWTGEPTTKHFSDIFLGRCLIYTQILRPEMRDQNCQEILSTFKGAFVSKNPCNITREDYAPLVKLVTQTIPCNKTLFWSKSKHLAHQYTWIQGKMFTLEDTLLGYIADDLRWCGDPSTSDMNYVSCPHWSENCPNNPITVFWKVISQKFAEDACGVVQVMLNGSLREPFYKNSTFGSVEVFSLDPNKVHKLQAWVMHDIEGASSNACSSSSLNELKMIVQKRNMIFACVDNYRPARFLQCVKNPEHPSCRLNT

• Full Name: CD38 antigen
• Calculated Molecular Weight: 34 kDa
• Observed Molecular Weight: 40-45 kDa
• GenBank Accession Number: NM_007646.5
• Gene Symbol: Cd38
• Gene ID (NCBI): 12494
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P56528
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).