• Featured Product
  • KD/KO Validated

CoraLite®488-conjugated CD38 Monoclonal antibody

CD38 Monoclonal Antibody for FC

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

FC

Conjugate

CoraLite®488 Fluorescent Dye

CloneNo.

3C6G4

Cat no : CL488-60006

Synonyms

ADP ribosyl cyclase 1, cADPr hydrolase 1, CD38, CD38 molecule, Cyclic ADP ribose hydrolase 1, T10



Tested Applications

Positive FC detected inDaudi cells
For other applications, we recommend the unconjugated version of this antibody, 60006-1-Ig

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

CL488-60006 targets CD38 in FC applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen CD38 fusion protein Ag0487
Full Name CD38 molecule
Calculated molecular weight 300 aa, 34 kDa
GenBank accession numberBC007964
Gene symbol CD38
Gene ID (NCBI) 952
Conjugate CoraLite®488 Fluorescent Dye
Excitation/Emission maxima wavelengths488 nm/515 nm
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

Background Information

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).

Protocols

Product Specific Protocols
FC protocol for CL488 CD38 antibody CL488-60006Download protocol
Standard Protocols
Click here to view our Standard Protocols