CD42c Polyclonal antibody

CD42c Polyclonal Antibody for WB, ELISA

Cat No. 55161-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

GP1BB, GPIbB, GPIb beta, GP Ib beta, Antigen CD42b beta

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inHuman peripheral blood platelets

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:8000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

55161-1-AP targets CD42c in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

fusion protein

Predict reactive species
Full Name glycoprotein Ib (platelet), beta polypeptide
Calculated Molecular Weight 43 kDa
Observed Molecular Weight 26 kDa
GenBank Accession NumberNM_000407
Gene Symbol CD42c
Gene ID (NCBI) 2812
RRIDAB_2881279
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDP13224
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CD42c, also known as platelet glycoprotein Ib beta chain (GP1BB), is a transmembrane protein containing a leucine-rich amino acid sequence (PMID: 3353370). CD42c is covalently linked to platelet glycoprotein Ib alpha chain (CD42b/GP1BA) to form GPIb, which is part of the Glycoprotein Ib-V-IX receptor (GPIb-V-IX) complex that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion (PMID: 7660135). Mutations in the GP1BB gene have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome, and giant platelet disorder.

Protocols

Product Specific Protocols
WB protocol for CD42c antibody 55161-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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