Mouse CD48 Recombinant antibody, PBS Only

CD48 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, ELISA
Cat No. 83871-1-PBS
Clone No.240732E3

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, IF/ICC, ELISA

MEM 102, CD48 antigen, BLAST1, BLAST 1, BLAST

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

83871-1-PBS targets CD48 in WB, IF/ICC, ELISA applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein Predict reactive species
Full Name CD48 antigen
Calculated Molecular Weight27 kDa
Observed Molecular Weight45-60 kDa
GenBank Accession NumberBAE96326.1
Gene Symbol Cd48
Gene ID (NCBI) 12506
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP18181
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

Signaling lymphocytic activation molecule family 2 (SLAMF2, CD48) is an adhesion and costimulatory molecule expressed constitutively on most hematopoietic cells, particularly in antigen-presenting cells (APC). CD48 is expressed on all the hematopoietic cells, both in humans and mice, except for murine neutrophils and long-term HSC. CD48 exists as both a membrane-bound (mCD48) and a soluble (sCD48) form. CD48 can activate T cells, antigen-presenting cells and granulocytes, by binding to CD2 or bacterial FimH, and through cell intrinsic effects. Interactions between CD48 and its high-affinity ligand CD244 are more complex, with both stimulatory and inhibitory outcomes. CD48 expression is increased in autoimmunity and allergy diseases, and anti-CD48 monoclonal antibodies have been shown to attenuate experimental autoimmune encephalomyelitis.

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