Anti-Human CD6 Rabbit Recombinant Antibody, PBS Only

CD6 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98223-1-PBS
Clone No.241965C9

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

241965C9, CD6 molecule, Soluble CD6, T12, T-cell differentiation antigen CD6

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

98223-1-PBS targets CD6 in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen CD6 fusion protein Eg2079 Predict reactive species
Full Name CD6 molecule
GenBank Accession NumberBC033755
Gene Symbol CD6
Gene ID (NCBI) 923
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP30203
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

CD6 is a type I transmembrane glycoprotein that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harboring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands.

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