CD83 Recombinant antibody, PBS Only

CD83 Uni-rAbTM Recombinant Antibody for Indirect ELISA

Cat No. 84796-2-PBS
Clone No.241855G2

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Indirect ELISA

B cell activation protein, B-cell activation protein, BL11, CD83 antigen, CD83 molecule

Formulation:  PBS Only
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

84796-2-PBS targets CD83 in Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen CD83 fusion protein Eg2033 Predict reactive species
Full Name CD83 molecule
Calculated Molecular Weight23 kDa
GenBank Accession NumberNM_004233.4
Gene Symbol CD83
Gene ID (NCBI) 9308
ENSEMBL Gene IDENSG00000112149
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ01151
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

CD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928).

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