|Positive FC detected in||BALB/c mouse thymocytes|
|This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.|
|Sample-dependent, check data in validation data gallery|
FITC-65088 targets CD90.2 in FC applications and shows reactivity with Mouse samples.
|Cited Reactivity||human, mouse|
|Host / Isotype||Rat / IgG2b, kappa|
|Immunogen||Mouse thymus or spleen|
|Full Name||thymus cell antigen 1, theta|
|GenBank accession number||BC054436|
|Gene ID (NCBI)||21838|
|Conjugate||FITC Fluorescent Dye|
|Excitation/Emission maxima wavelengths||494 nm / 520 nm|
|Purification Method||Affinity purification|
|Storage Buffer||Phosphate based buffer with 0.09% sodium azide and 0.1% gelatin, pH 7.2.|
|Storage Conditions||Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.|
CD90 (Thy-1) is a 25 kDa, GPI-linked membrane glycoprotein that belongs to immunoglobulin superfamily (PMID: 6177036; 6153212). Originally described as a brain thymus cross-reactive antigen, it is found in large quantities on mouse and rat thymocytes and central nervous system cells (PMID: 83175). CD90 has been postulated to be involved in cellular recognition, adherence, and T cell activation (PMID: 7683034). Mouse CD90 (Thy-1) is defined as a differentiation alloantigen, represented as two serologically distinguishable allelic forms, designated CD90.1 (Thy-1.1) and CD90.2 (Thy-1.2) (PMID: 83175). CD90.2 is expressed by thymocytes, T cells, neurons and hematopoietic stem cells in most strains of mice (C3H, BALB/c, C57BL/6, DBA, and others), whereas CD90.1 is expressed in some mouse strains like AKR (PMID: 5919593).
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