Product Information
88426-1-PBS targets CDC25B in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Ag0994 Product name: Recombinant human CDC25B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-300 aa of BC006395 Sequence: MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKT Predict reactive species |
| Full Name | cell division cycle 25 homolog B (S. pombe) |
| Calculated Molecular Weight | 65 kDa |
| Observed Molecular Weight | 60 kDa |
| GenBank Accession Number | BC006395 |
| Gene Symbol | CDC25B |
| Gene ID (NCBI) | 994 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P30305 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
CDC25B, also named CDC25HU2, belongs to the MPI phosphatase family. It is a tyrosine protein phosphatase that functions as a dosage-dependent inducer of mitotic progression. CDC25B directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
