Product Information
31526-1-PBS targets CDC42BPB in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag35745 Product name: Recombinant human CDC42BPB protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1530-1711 aa of NM_006035.3 Sequence: SGAVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAVPPSQEERPGPAPTNLARQPPSRNKPYISWPSSGGSEPSVTVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLEQPACDT Predict reactive species |
| Full Name | CDC42 binding protein kinase beta (DMPK-like) |
| Calculated Molecular Weight | 194 kDa |
| Observed Molecular Weight | 194 kDa |
| GenBank Accession Number | NM_006035.3 |
| Gene Symbol | CDC42BPB |
| Gene ID (NCBI) | 9578 |
| RRID | AB_3670021 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9Y5S2 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
CDC42BPB is a serine/threonine protein kinase and codes for MRCKβ (myotonic dystrophy-related Cdc42-binding kinase beta), a regulator of cell cytoskeletal reorganization and cell migration. CDC42BPB shows expression in the granule cell layer of the lateral adult cerebellum, which has been associated with cognitive functions, and has recently been associated with neurodevelopmental disorders including ASD (autism spectrum disorder). (PMID: 35942939)
