Anti-Mouse CEACAM1/CD66a Rabbit Recombinant Antibody, PBS Only

• 

  FC experiment of mouse splenocytes using 98185-1-RR (same clone as 98185-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CEACAM1/CD66a Rabbit Recombinant Antibody (98185-1-RR, Clone: 241856H5) or 0.25 ug Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD45R. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98185-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 98185-1-RR (same clone as 98185-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CEACAM1/CD66a Rabbit Recombinant Antibody (98185-1-RR, Clone: 241856H5) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD45R. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98185-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98185-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98185-1-RR against Mouse CEACAM1/CD66a were performed. The affinity constant is below 1 pM.

CEACAM1/CD66a Uni-rAb^® Recombinant Antibody for FC

Cat No. 98185-1-PBS

Clone No.241856H5

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Synonyms

Biliary glycoprotein D, Biliary glycoprotein 1, BGP-1, Bgp1, Bgp

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Product Information

98185-1-PBS targets CEACAM1/CD66a in FC applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Recombinant protein

• Full Name: carcinoembryonic antigen-related cell adhesion molecule 1
• Calculated Molecular Weight: 57 kDa
• Gene Symbol: Ceacam1
• Gene ID (NCBI): 26365
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P31809-1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530).