Tested Applications
| Positive FC detected in | human peripheral blood leukocytes |
Recommended dilution
| Application | Dilution |
|---|---|
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
98061-1-RR targets CEACAM1/3/6 (CD66a/c/d) in FC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Recombinant protein Predict reactive species |
| Full Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| Calculated Molecular Weight | 526 aa, 58 kDa |
| GenBank Accession Number | BC014473 |
| Gene Symbol | CEACAM1 |
| Gene ID (NCBI) | 634 |
| RRID | AB_3672208 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P13688 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2 - 8°C. Stable for one year after shipment. |
Background Information
CEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530). This antibody is raised against 35-428 aa of human CEACAM1/CD66a and can cross-react with CEACAM6/CD66c and CEACAM3/CD66d.
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for CEACAM1/3/6 (CD66a/c/d) antibody 98061-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The Anti-Human CEACAM1/3/6 (CD66a/c/d) Rabbit Recombinant Antibody (Cat# 98061-1-RR) has 1 citation to date. It was cited in Translational Cancer Research (2026), in a study on spatial immune profiling of local tissues and peripheral blood cytokines in lung squamous cell carcinoma patients with immune-related pneumonitis. The research field is oncology/immunology, specifically lung cancer and immune response.
| Species | Application | Title |
|---|---|---|
Transl Cancer Res Spatial immune profiling of local tissues and its correlation with peripheral blood cytokines in lung squamous cell carcinoma patients with immune-related pneumonitis. |
