CFAP45 Recombinant monoclonal antibody, PBS Only (Capture)

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• CFAP45 Recombinant monoclonal antibody, PBS Only (Capture) (88026-3-PBS)

CFAP45 Uni-rAb^® Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Cat No. 88026-3-PBS

Clone No.260397E3

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Cytometric bead array, Indirect ELISA

Synonyms

CCDC19

• 

  WB analysis using 88026-3-RR (same clone as 88026-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 88026-3-RR (CFAP45 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88026-3-PBS in a different storage buffer formulation.

• 

  Cytometric bead array sample test of MP03337-1

  The mean CFAP45 concentration was determined to be 85.2 ng/mL in mouse testis tissue extract based on a 4.2 mg/mL extract load, mouse spleen tissue extract were served as a negative control.

• 

  Cytometric bead array standard curve of MP03337-1

  Cytometric bead array standard curve of MP03337-1, CFAP45 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 88026-3-PBS. Detection antibody: 88026-2-PBS. Standard: Ag16633. Range: 0.078-10 ng/mL.

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Product Information

88026-3-PBS targets CFAP45 as part of a matched antibody pair:

MP03337-1: 88026-3-PBS capture and 88026-2-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag16633

  Product name: Recombinant human NESG1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 202-551 aa of BC027874

  Sequence: KCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERIDEIKRKKLEELRATGLPEKYCIEAERKANILPATSVN

• Full Name: coiled-coil domain containing 19
• Calculated Molecular Weight: 551 aa, 66 kDa
• GenBank Accession Number: BC027874
• Gene Symbol: CCDC19
• Gene ID (NCBI): 25790
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9UL16
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CCDC19, also named as NESG1, CFAP45, is specifically expressed in human nasopharynx and trachea, and decreased or absent in nasopharyngeal carcinoma (NPC) tissues and cell lines. In addition, the levels of NESG1 protein are significantly greater in the low-grade NPC tissues than that in the high-grade NPC tissues. NESG1 also significantly regulats the expression of cell cycle regulators CCNA1 and p21. NESG1 may act as a tumor suppressor by inhibiting cell proliferation, invasion and migration of NPC cells.