CHRDL1 Polyclonal antibody

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  WB analysis using 15390-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 15390-1-AP (CHRDL1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

CHRDL1 Polyclonal Antibody for WB, ELISA

Cat No. 15390-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

CHL, chordin like 1, Chordin like protein 1, Chordin-like protein 1, dA141H5.1

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Tested Applications

• Positive WB detected in: mouse retina tissue, rat brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

15390-1-AP targets CHRDL1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag7549

  Product name: Recombinant human CHRDL1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 107-456 aa of BC002909

  Sequence: NNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC

• Full Name: chordin-like 1
• Calculated Molecular Weight: 51 kDa
• Observed Molecular Weight: 51 kDa
• GenBank Accession Number: BC002909
• Gene Symbol: CHRDL1
• Gene ID (NCBI): 91851
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9BU40
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CHRDL1, also known as Chordin-like 1, is a gene located on the X chromosome that encodes a protein which acts as an antagonist of bone morphogenetic proteins (BMPs). BMPs are involved in various developmental processes, and CHRDL1's role in antagonizing them is crucial for proper development and homeostasis. Mutations in CHRDL1 can lead to conditions like X-linked megalocornea.